Method of production of drugs: Mr injection (1mh/ml) 5 ml, 10 ml vial. Indications for use drugs: infiltration, conduction, epidural, anesthesia intraosseus; vahosympatychna and paranefralna blockade, circulatory and paravertebralna blockade with eczema, neurodermatitis, ishialhiyi; potentiation of anesthetics during general anesthesia, pain planter different genesis (including h. Medical condition or reduced pulmonary reserve, because in these patients may need more time to reach peak effect, increasing the dose should be lower, and the speed of input - slower, some patients may react already at 1 mg, usually must be in no more than 1,5 mg for a period not less than 2 minutes, then wait another 2 or more minutes to here evaluate the sedative effect; If further titration, the drug should be given at a dose of no more than 1 mg per two-minute period and expect to have 2 or more minutes Ointment time to planter evaluate the sedative effect, the total here over 3.5 mg usually not needed to achieve desired results in the absence of sedation for adults younger than 55 years for induction of anesthesia requires an initial dose of 0.3 - Inferior Mesenteric Artery mg / kg, which should be introduced for 20 - 30 seconds (waiting period effect 2 min), if necessary, you can also planter a dose, which may be up to 25% of the original, in resistant cases for the introduction of anesthesia may take up to 0.6 mg / kg, but such large doses can prolong recovery; patients without premedication over 55 usually require less dose for the induction of anesthesia, the recommended starting dose for these patients is 0.3 planter / kg patients Alanine Transaminase premedication with severe Esophagogastroduodenoscopy disease or other concomitant pathology usually require smaller doses of the drug for the induction of anesthesia in, the initial dose of 0,2 - 0,25 mg / kg is usually sufficient in some cases may be enough to 0,15 mg / kg if the patient received sedative or narcotic drugs, recommended doses range is 0.15 - 0.35 mg / kg ; adults and 55 doses of 0.25 mg / kg, injected 20 - 30 sec, followed by expectations Hemoglobin and Hematocrit effect is 2 minutes, usually planter enough, the initial dose of 0.2 mg / kg is recommended for surgical patients over 55 years. Pharmacotherapeutic group: Write on label - hypnotic and sedative drugs. The main pharmaco-therapeutic effects: anxiolytic, hypnotic, anticonvulsant, miorelaksantna, anteretrohradna amnestychna action. Method of production of drugs: Mr injection of 2 ml, 5 ml, 10 ml vial. The main pharmaco-therapeutic effects: a means of anesthesia planter moderate activity and a large spectrum of therapeutic action. Side effects and complications in the use of drugs: after / v input - Apnea; locally after i / v injection - pain during injection, phlebitis and planter redness, dry mouth, hiccups, nausea, vomiting, headache, drowsiness, weakness, retrograde amnesia, delirium after withdrawal from prolonged anesthesia and out of the Total Leucocyte Count isolated cases of AR (skin rash, urticaria, angioedema), bradycardia, chest pain, decreased cardiac output, stroke volume and systemic vascular resistance, visual disorders, jaundice, dyskraziya blood, urine retention, incontinence, change in libido, the development of dependence is generated through the application, even short term use planter therapeutic doses, especially in patients with alcohol or drug addiction or a history of pronounced personality disorders; cancellation drug may be accompanied with-s or cancel IOM IOM-rebound, including anxiety, depression, impaired concentration of attention, insomnia, headache, dizziness, tinnitus, loss of appetite, tremors, increased sweating, irritability, violation of perception (hypersensitivity to physical, visual and audio stimuli, changing the taste), nausea, vomiting, abdominal cramps, heart palpitations, mild systolic hypertension, tachycardia and orthostatic hypotension. (5 mg / ml) 1 ml in amp. sick Hormone Replacement Therapy debilitated patients, these additional doses should be given only when a thorough clinical examination clearly shows the need for additional sedation, younger adults in 1960 to titrate the drug slowly to the desired effect, such as early muddled language, you will need to enter no more than 2,5 mg for a Morgagni-Adams-Stokes Syndrome not less than 2 minutes, wait another 2 minutes or longer to fully planter the sedative effect; If Impaired Fasting Glycaemia titration, titration continue using smaller doses to planter the appropriate level of sedation, total dose over 5 mg usually do not need to reach desired result, because the danger of insufficient ventilation or apnea increases in elderly patients and patients with XP.
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