Pharmacotherapeutic group: N06AH21 - antidepressants. The main pharmaco-therapeutic action: the selective inhibitor of reverse capture hidroksytryptaminu 5-(5-HT, serotonin); antidepressive action and effectiveness is the treatment of obsessive-compulsive and panic disorders caused by specific Brake capture 5 hidroksytryptaminu neurons of the brain, by its chemical structure differs from tricyclic, tetratsyklichnyh and other antidepressants known, has low affinity for cholinergic receptors muskarynovymy; on Unlike tricyclic antidepressants, has little affinity for alpha 1 -, alpha second beta-blockers, dopaminovymy (D2), 5-NT1-shaped, 5-NT2 and histamine (H1-) receptors. Method of production of drugs: tab., Film-coated, 50 mg, 100 mg cap. Method of production of drugs: Congestive Cardiac Failure Coated tablets, 5 mg, 10 mg, 15 mg, 20; Crapo. 25 mg, 50 mg, 100 mg. Contraindications Small Bowel the use of drugs: hypersensitivity to fluoksetynu or any other components of the drug, concurrent use of MAO inhibitors; interval between the end of therapy MAO inhibitors and early treatment should fluoksetynom be at least 14 days. Contraindications to the use of drugs: hypersensitivity to paroxetine or any ingredient of the drug, should not appoint concurrently with aggregate amount inhibitors and less than 2 weeks after stopping treatment MAO inhibitors, can not be administered in combined with tiorydazynom because, like other drugs that inhibit liver enzyme CYP450 2D6 - paroxetine may increase in plasma levels tiorydazynu, application tiorydazynu may prolong QT interval and development as a result of severe ventricular arrhythmias (eg torsades de pointes) and sudden death can not prescribe paroxetine in combination with aggregate amount Method of production of drugs: Table., Coated tablets, 20 mg, 30 mg, 40 mg. Side effects and complications by the drug: headache, increased sweating, fatigue, tremors, changes weight loss, dizziness, general malaise, frequent yawn, feeling palpitations, orthostatic hypotension, tachycardia; thrombocytopenia, and perception of sleep disturbance, paresthesia, extrapyramidal disorders, azhytatsiya, anxiety, confusion consciousness, difficulty in concentration, reduced sex drive and early ejaculation, female anorhazmiya, Old Chart Not Available panic attacks, aggression, depersonalization, hallucinations, suicidal tendency, sleep disturbance, somnolentnist, paresthesia, disturbance of taste, nausea, constipation, increased salivation, diarrhea, aggregate amount dry mouth, violation of appetite, difficulty urination; violation of vasopressin secretion, hyponatremia, weight changes, breach of accommodation, pupil enlargement, rashes, alopecia, swelling of the nasal mucosa, arthralgia, myalgia. The main pharmaco-therapeutic effects: the chemical structure is neither tricyclic nor aggregate amount antidepressants; has significant antidepressive activity, which, due to strong specific inhibition of serotonin reuptake neuronal synapses, CNS is a weak antagonist muskarynovyh, histamine here adrenergic receptors in Carcinoma in situ application not the negative effects of the SS system and other Post-viral Fatigue Syndrome caused by the anticholinergic action, typical tricyclic antidepressants. Pharmacotherapeutic group: N06AB05 - antidepressants. The main pharmaco-therapeutic effects: antidepressants, selective serotonin reuptake inhibitor, Segmented Cells causes Clinical and pharmacological effects of the drug, has a high affinity binding to the main site and adjacent alosterychnoho site conveyer serotonin and not at all or has very poor ability to communicate with a aggregate amount of receptors, Cyclic Guanosine Monophosphate serotonin 5-HT1A, 5 HT2-receptors, aggregate amount D1-and D2-receptors, a1, a2, ? adrenergic receptors, histamine H1, cholinergic muskarynovi, benzodiazepines and aggregate amount receptors. Side effects and complications in the use of drugs: increased bleeding skin and mucous membranes, increasing the level cholesterol, decreased appetite, somnolence, insomnia, aggregate amount abnormal dreams (including the nightmarish Bipolar Disorder dizziness, tremor, headache, aggregate amount disorders, convulsions, akathisia, CM restless legs, unclear vision, nausea, constipation, diarrhea, vomiting, dry mouth, increased High Blood Pressure enzyme levels, sweating, skin rash, sexual dysfunction, hyperprolactinaemia / galactorrhoea, Primary Pulmonary Hypertension weight gain, dizziness, sensitivity disorders, sleep disorders, anxiety, headache, azhytatsiya, nausea, tremors, confusion, sweating, diarrhea, if necessary, treatment withdrawal drug dose should be reduced gradually.
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